The principle constituents of Aloe vera are anthraquinones (aloe-emodin and aloin barbalin), cinnamoyl, pcoumaroyl, feruloyl, caffeoyl aloesin, aloemannan, acemannan, verectin, and bisbenzopyran. The composition of Vetiveria zizanoides are valencene, octadecenamide, hexamethyl-tetracosahexaene, benzendicarboxylic acid, and diisooctyl ester.
The principle ingredient of Curcuma longa is curcumin, demethoxycurcumin and bisdemethoxycurcumin. Citrus limon contains sugars, polysaccharides, organic acids, lipids, myo-inositol, carotenoids, vitamins, minerals, flavonoids, limonoids (limonin and nomilin), volatile oil, alpha-terpinene, alpha-pinene, citral, coumarins, mucilage, pectins and bioflavonoids (eriocitrin and hesperidan). Orange leaves contain an essential oil in which the two terpenoids linalool and β-elemene are found as main constituents.
The principle ingredient of Crocus sativus is a carotenoid (Crocetin).
The principle ingredients of Myristica fragrans are myristicin, licaricin and malabaricone (B and C).
Clinical Pharmacology
Melatru cream improves the skin by acting on the melanocytes. Melatru also cleanses, nourishes and regenerates the skin surface. The anti-pruritic, anti-bacterial and anti-fungal properties control the complications. Melatru cream is proficient in preventing UV rays damage and arrests premature aging.
Indications
Melasma and restoration of complexion.
Contraindications
Hypersensitivity to any of the ingredients.
Adverse Effects
None.
Special Precautions
Do not rub vigorously on inflamed skin surface.
Dosage
To be applied twice a day.
Directions for use: Take sufficient quantity and rub gently on the skin so that the skin is completely greased after the cream has been rubbed in.
Presentation
30 g lamitube.
References
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Fukai, T. and Nomura, T. Phytochemistry, 1995, 38, 759.
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Haraguchi H, Yoshida N. Pharm Pharmacol. 2000 Feb; 52(2): 219-23.
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Kanzonol X, T. Fukai. Phytochemistry, 1996, 43, 1119.
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T. Kinoshita, K. Kajiyama. Heterocycles, 1996, 43, 581.
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Li W, Asada Y, Yoshikawa. T. Phytochemistry.2000 Nov; 55(5): 447-56.
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Qureshi S, Rai MK, Agrawal SC. Bull. 1997, 3(1-4): 56-60.
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Lami N, Kadota S. Chem Pharm Bull (Tokyo). 1991 Jun; 39(6): 1551-5.
Huang J, Li H, Yang J, Chen Y, Liu Y, Li N, et al. Chemical components of Vetiveria zizanioides volatiles. Ying Yong Sheng Tai Xue Bao. 2004; 15(1): 170-172.
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Suekawa, M, Ishige. J Pharmacobiodyn 7, 836-848.
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Yoshikawa M et al. Yakugaku zasshi, 1993, 113:307-315.
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Kostalova D, Bezakova L. Ceska Slov Farm. 2004 Sep; 53(5): 248-51.
