OSTRANIL CAPSULE

Buy

A multipronged approach to arthritis management

Each 500 mg capsule contains

Anantamul (Hemidesmus indicus)	100 mg
Shetverenda (Ricinus communis)	100 mg
Sajina (Moringa pterygosperma)	100 mg
Gulancha (Tinospora cordifolia)	125 mg
Rakta Punarnaba (Boerhaavia diffusa)	75 mg

The principle ingredients of Hemidesmus indicus are pentacyclic triterpenes including oleanenes (olean-en-betayl acetate, and olean-en-alpha-yl acetate), ursenes (seco-urs-dien-alpha- H-beta-yl actetate, urs-en-beta-H-beta-yl acetate, seco-urs-dien-alpha-Hbeta- ol, a lupene (lup-dien-on-ol), beta-amyrin acetate¹, pregnane glycosides, denicunine, heminine², pregnane oligoglycosides, medidesmine, hemisine and desmisine³. Ricinus communis is primarily made from ricinoleic acid. The major bioactive compounds of Moringa pterygosperma are phenolics of flavonoids (quercetin and kaempferol) ⁴. The active constituents of Tinospora cordifolia are diterpene glucosides (A-D) ⁵, cordioside, cordiofolioside (A-C) ⁶, cordiol, syringin⁷, diterpene furanolactones tinosporide⁸ and columbin⁹. The principle ingredients of Boerhaavia diffusa are eupalitin-O-beta-D-galactopyranoside, eupalitin¹⁰, liriodendrin and syringaresinol mono-beta-D-glucoside¹¹.



Ostranil addresses its action at COX2 isoenzyme. It inhibits the oxidative depolymerization of hyaluronic acid and thus helps to protect synovial fluid in the joints. Ostranil capsule significantly inhibits xanthine oxidase enzyme which reduces uric acid production and thus is highly beneficial in gout. Ostranil capsule has ROS scavenging ability which prevents damaging side effects of chronic inflammation.

The capsule is clinically validated for safety and efficacy and is safe for long term use owing to its hepatoprotective function. Ostranil promotes secretion of cytoprotective mucus in the intestine to prevent mucosal damage. The capsule does not cause gastric irritation or renal damage and is free from cardiovascular side effects even on long term usage.



Rheumatoid arthritis, osteoarthritis, gout, spondylosis, and ankylosing spondylitis.



Hypersensitivity to any of the ingredients.



Not found in multi-centric clinical trials. May safely be continued for a longer period.



None.



1-2 capsules thrice a day or as directed by the physician



Container of 60 capsules.

1	Roy SK. Pharmazie. 2001 Mar; 56(3):244-6.
2	Sigler P. Phytochemistry. 2000 Aug; 54(8):983-7.
3	Deepak D. Phytochemistry. 1997 Jan; 44(1): 145-51.
4	Siddhuraju P, Becker K. J Agric Food Chem. 2003 Apr 9; 51(8): 2144-55.
5	Maurya R, Manhas LR. Phytochemistry. 2004 Jul; 65(14): 2051-5.
6	Gangan VD, Pradhan P. Phytochemistry. 1994 Oct; 37(3): 781-6.
7	Kapil A, Sharma S. J Ethnopharmacol. 1997 Oct; 58(2): 89-95.
8	Swaminathan K, Sinha U C. Acta Crystallogr C. 1989 Jan 15; 45 (Pt 1): 134-6.
9	Swaminathan K, Sinha U C. Acta Crystallogr C.1989 Feb 15; 45 (Pt 2): 300-3.
10	Pandey R. Int Immunopharmacol. 2005 Mar; 5(3):541-53.
11	Lami N. Chem Pharm Bull (Tokyo). 1991 Jun; 39(6):1551-5.