 |
A unique choice for dry and productive cough |
Composition
Each 5 ml contains
| Madhu (Meldespumatum) |
250 mg |
| Tulsi (Ocimum sanctum) |
25 mg |
| Pippali (Piper longum) |
25 mg |
| Haridra (Curcuma longa) |
25 mg |
| Mulethi (Glycyrrhiza glabra) |
20 mg |
| Sunthi (Zingiber officinalle) |
15 mg |
| Vasaka (Adhatoda vasica) |
10 mg |
| Pudina (Mentha piperita) |
2 mg |
Phytochemistry
The principle ingredients of
Meldespumatum are flavonoids, phenolic acids (caffeic and ferulic acid), and hydrogen peroxide
1. The principle ingredients of
Ocimum sanctum are cirsilineol, cirsimaritin, isothymusin, isothymonin, apigenin, rosmarinic acid, eugenol
3, orientin, vicenin
4, oleanolic acid and ursolic acid
5.
Adhatoda vasica vasica is primarily made of alkaloids vascine and vascionine
6. The principle ingredients of
Glycyrrhiza glabra are prenylated dihydrostilbenes, flavonoids (glabranin, pinocembrin, licoflavone, wighteone, licoagrodin)
7, prenylated retrochalcones, licoagrochalcones, prenylated aurone, licoagroaurone, licochalcone C, kanzonol Y, glyinflanin B and glycyrdione A7, licochalcone A
8, and glydernine
9.
Clinical Pharmacology
Tuswas exerts its therapeutic benefits by its anti-tussive, mucolytic, anti-allergic, bronchodialatory, anti-inflammatory, anti-microbial, anti-oxidant and immune-stimulant activities.
Meldespumatum has potent anti-bacterial activity against upper respiratory tract pathogens and also acts as a soothing agent in dry cough. Vitis vinifera has strong nitric acid synthase inhibitory activity.
Ocimum sanctum has strong antimicrobial, anti-allergic and anti-oxidant actions. Adhatoda vasica has anti-tussive action comparable to codeine and also mucolytic and anti-allergic actions. Glycyrrhizin from
Glycyrrhiza glabra is a potent inhibitor of 11-betahydroxysteroid dehydrogenase, which is beneficial in steroid-dependent asthma and causes bronchodialatory action.
Indications
Allergic cough, dry cough, smoker’s cough and cough with expectoration.
Contraindications
There are no absolute contraindications in the use of Tuswas syrup.
Adverse Effects
Tuswas syrup has no short- and long-term effects if taken as per the prescribed dosage.
Special Precautions
If there is no improvement in the cough even after 3 days, thorough check up is advised.
Dosage
Adult: 1 – 2 tsp thrice daily
Children: 1 tsp thrice daily
Presentation
Pilfer-proof bottles of 100 ml.
References
| 1 |
Wahdan HA. Infection. 1998 Jan-Feb; 26(1): 26-31. |
| 2 |
Yilmaz Y. J Agric Food Chem. 2004 Jan 28; 52(2):255-60. |
| 3 |
Kelm MA. Phytomedicine. 2000 Mar; 7(1):7-13. |
| 4 |
Uma Devi P. Radiat Res. 2000 Oct; 154(4): 455-60. |
| 5 |
Balanehru S. Biochem Int. 1991 Jul; 24(5): 981-90. |
| 6 |
Gupta OP. Indian J Med Res. 1977 Oct; 66(4): 680-91. |
| 7 |
Li W. Phytochemistry. 2000 Nov; 55(5):447-56. |
| 8 |
Fu Y, Hsieh. Biochem Biophys Res Commun. 2004 Sep 10; 322(1):263-70. |
| 9 |
Azimov MM. Farmakol Toksikol. 1988 Jul-Aug; 51(4):90-3. |
| 10 |
Kapil A. J Ethnopharmacol. 1997 Oct; 58(2): 89-95. |
| 11 |
Hallstrom H. Nat Toxins. 1997; 5(5):186-92. |
| 12 |
Kim YB. Arch Pharm Res. 1991 Mar; 14(1):1-6. |
| 13 |
Qiu Q. Zhong Yao Cai. 2004 Nov; 27(11): 823-6. |
| 14 |
Orabi KY. J Nat Prod. 1991 May-Jun; 54(3): 856-9. |
| 15 |
Johri RK J Ethnopharmacol. 1992 Sep; 37(2): 85-91. |
| 16 |
Hao K. Pharmazie. 2005 Jan; 60(1):69-71. |
| 17 |
Matsuda H. Chem Pharm Bull (Tokyo). 2004 Oct; 52(10):1200-3. |